This research investigates how to optimize mRNA transfection in human T-cells utilizing the jetMESSENGER ® transfection reagent ... setting the standards for single-use products that are ...

Transfection is a crucial non-viral technique for introducing DNA or RNA into cells, yet achieving high efficiency ... Below, we delve into strategies and recent advancements in transfection reagents ...

But to date this technology -- which allows scientists to use a 'guide' RNA to modify DNA sequences and evaluate the effects -- is able to target, delete, replace, or modify only single gene ...

A critical feature of CRISPR-based genome editing is its straightforward programmability, as the CRISPR guide RNA (gRNA) molecule alone can ... and prepared with a transfection reagent (Lipofectamine ...

Under this agreement, the two companies will collaborate on the development, optimization, and application of transfection reagents, with the goal of providing biopharmaceutical customers with ...

In this guide, we will explore why nucleic acid quantification is important, the differences between DNA and RNA and the methods used to quantify and assess the purity of DNA and RNA. DNA ...

To identify factors that might regulate viral mRNA translation, we developed a technique for identifying proteins associated with a native RNA expressed from its endogenous promoter and genomic locus.

We demonstrated that L1 transfection ... Primary antibodies: DNA-RNA Hybrid (mouse, Merck Millipore, MABE1095), dsRNA (mouse, Merck Millipore, MABE1134). Cells were harvested and resuspended in 1 ml ...

Named Sc-SPORT for Single Cell Structure Probing Of RNA Transcripts, this new approach is able to identify biomarkers crucial for human development and disease, based on shape rather than sequence ...

The SBiB reagent enables researchers to incorporate multiple initiators anywhere in a DNA or RNA sequence during solid-phase synthesis. Previously it was only feasible to incorporate a single ...