WebMD1mon
Bridge RNAs: ‘Holy Grail’ in Next-Gen Gene Editing Tech?
When his team began investigating, the researchers discovered a new type of guide RNA that acts like a bridge ... blood disorder is caused by a single mutation. Compare that with a disease like ...
chromatographyonline12d
Understanding the On-off Retention Mechanism of Oligonucleotides
A team from the University of Geneva and Bayer AG present their findings on the on-off retention of oligonucleotides and the ...
Computational tool incorporates transcriptome size to improve RNA-seq analysis
Researchers studying gene expression have access to vast amounts of data from cells or tissues. This is thanks to advances in ...
Nature4d
CRISPR-Cas systems articles from across Nature Portfolio
Such screens genetically perturb many genes in parallel and use single-cell RNA sequencing to assess the ... transposon-based delivery of the CRISPR guide RNAs. Prime editing systems (PEs) hold ...
mskcc.org6y
RNA Decay
Our investigations of exosomes in budding yeast revealed that its central channel is essential, and that it functions to guide ... optimized DNA-RNA chimera that stalls the MTR4 helicase during ...
Nature5d
Molecular biology articles from across Nature Portfolio
Such screens genetically perturb many genes in parallel and use single-cell RNA sequencing to assess the ... transposon-based delivery of the CRISPR guide RNAs. The selective destruction of ...