disordered regions provide order to chemokines-GPCR pairs The scientists uncovered how chemokines and their receptors bind select members of the GPCR family by data mining protein sequences and ...

Department of Structural Biology The scientists uncovered how chemokines and their receptors bind select members of the GPCR family by data mining protein sequences and structural information.

Scientists at St. Jude Children’s Research Hospital and the Medical College of Wisconsin have discovered how chemokines and G ...

The first important observation he made was that new protein synthesis is required for CSR. That finding led us to set up subtractive hybridization to isolate the cDNA encoding the switch ...

The scientists uncovered how chemokines and their receptors bind select members of the GPCR family by data mining protein sequences and ... turning down a signal that normally stops their movement.

The authors confirm that telomeres in telomerase-positive cells terminate with 5'-ATC in a Pot1-dependent manner, and demonstrate that this principle holds true in telomerase-negative ALT cells as ...

Their findings, published in Nature Human Behavior, suggest that this encoding unfolds via a sequence of stable neural states. "When we started this project in 2022, we initially aimed to ...

This valuable study presents an analysis of evolutionary conservation in intrinsically disordered regions, identified as key drivers of phase separation, leveraging a protein language model. The ...

Details and references regarding individual diseases are provided in the Supplementary Appendix. CIDP denotes chronic inflammatory demyelinating polyneuropathy, Covid-19 coronavirus disease 2019 ...

May 7, 2025 — Parasites are crucial indicators of ecosystem health, and their absence can signal trouble. Once pristine, Florida's Indian River Lagoon (IRL) now faces pollution and algal blooms ...

From peptide serums to moisturisers, and even lip treatments (a la rhode), they've become the most coveted ingredient to supercharge your skincare routine. As to the reason why? 'Signal peptides ...