Sertoli cell-only syndrome is a condition where the seminiferous tubules in the testes only hold Sertoli cells, “nurse” cells that assist in the production of sperm, causing infertility.

Testosterone, essential for spermatogenesis, is synthesized and secreted by the Leydig cells in response to stimulation by LH. FSH and testosterone act synergistically on Sertoli cells to promote ...

In mice, the Cdc42 gene is necessary for the correct polarity of Sertoli cells that support sperm production, according to a new study. Findings may accelerate efforts to create a non-invasive ...