Sertoli cell-only syndrome is a condition where the seminiferous tubules in the testes only hold Sertoli cells, “nurse” cells that assist in the production of sperm, causing infertility.

In mice, the Cdc42 gene is necessary for the correct polarity of Sertoli cells that support sperm production, according to a new study. Findings may accelerate efforts to create a non-invasive ...

But unlike normal sperm cells, these round cells also contained proteins normally made by sertoli cells that usually serve to nurture the growth of sperm. Together, the findings suggest that most ...

RESULTS: Spermatozoa were found on TESE in 15 (65.2%) of 23 men. On histopathology, the predominant pattern observed was Sertoli cell only (47.8%), followed by hypospermatogenesis (30.4%), mixed (17.4 ...