Thus, Syngap1 mutations linked to the human disorder accentuate motor feedback into a sensory cortex that improperly codes for touch experiences." In the mouse model examined by Rumbaugh and his ...

A research team has identified the primary cause of sensory hypersensitivity in a mouse model of autism spectrum disorders (ASD). A research team led by Director KIM Eunjoon of the Center for ...

"The aggregates then spread to other regions in the brain, and affect motor areas ... contributions to sensory impairments in a human alpha-synuclein transgenic mouse model of Parkinson's ...

After determining that the part of the brain that contains the highest amount of serotonin neurons was less active in the ASD model mice than in wild-type mice, the group examined a sensory region of ...

However, a new study shows that the thalamus, a relay station for incoming motor and sensory information ... examined the visual system of mice. This is a popular model for studying plasticity ...

“The mice required significant external sensory cues to pass the mirror test ... “Now that we have this mouse model, we can manipulate or monitor neural activity to comprehensively investigate ...

then confirmed it in a mouse model of ALS. “Our results firmly establish inhibition of the DP1 receptor as a therapeutic target for ALS," the authors wrote. Researchers have long suspected that the ...

Notably, an existing model slightly overexpressing this same mutant under control of the mouse prion promoter develops ALS-like motor neuron loss (Arnold et al., 2013). The new CRISPR Q331K-TDP-43 ...