Additionally, the scientists unexpectedly captured for the first time a detailed picture of how the "engine" driving the cellular replication machinery moves along DNA in human cells. Their ...

By knocking out TEFM, they observed a notable reduction in mtDNA copy number, alongside a decrease in 7S DNA levels and strand-asynchronous replication intermediates. These findings suggest that TEFM ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind ...

If parent cells and their daughter cells are to share a stable identity, parent cells must divide—and replicate their DNA—while ensuring that their histones are distributed properly to their ...

The findings visualize for the first time a molecular complex -- called CTF18-RFC in humans and Ctf18-RFC in yeast -- that loads a 'clamp' onto DNA to keep parts of the replication machinery from ...

Brandt Eichman and Walter Chazin, professors of biochemistry, have worked together to provide a better understanding of how exactly DNA replication is initiated in eukaryotes. Using Vanderbilt's ...

Abstract: Self replication is a kind of self-assembly in which a desired structure is obtained automatically from simple parts. We propose self-replication not by controlling the parts directly, but ...

But Surman points out that there are limitations to the self-replication; specific DNA chains are required as raw material for the process to work, as well as certain organic molecules ...

Researchers have gained a clearer insight into how common alterations to the structure of DNA affect the process of DNA replication. These structural changes can put a stop to replication, causing ...

DNA replication is a semi-conservative process, where half of the newly synthesized strands (daughters) are derived from the original strands (mothers). The confirmation of semi-conservative ...

Researchers have gained a clearer insight into how common alterations to the structure of DNA affect the process of DNA replication. These structural changes can put a stop to replication, causing ...

This process is called semi-conservative replication and is essential as it permits genetic information to be transmitted from generation to generation. The activities of both DNA polymerases are ...