Beneath the surface of present-day western Honduras lie the ruins of Copán—an archaeological site that once stood as a vital ...

In this paper, we study various policies for updating derived data and apply a mixed method for updating derived data based on a management approach to Quality of Service (QoS) using a semi-total ...

Three key mechanisms – DNA replication, telomere maintenance, and DNA repair – confer cells the ability to transmit their genomic information through generations. Some of these molecular pathways ...

The binding parameters of ethidium bromide (EtBr) with DNA of various GC/AT ratios were determined using ... The non-fluorescent complex is referred to semi-intercalative binding of EtBr. The binding ...

Department of Molecular Biology, Kyushu University Graduate School of Pharmaceutical Sciences, Fukuoka, Japan ...

This study finds these bacteria as the first example of an organism using ADP-ribose modification of DNA as a mechanism for regulating gene transcription and cellular replication. The ...

Precise replication of genetic material is essential to maintain genome stability. DNA replication is a tightly regulated process that ensues faithful copies of DNA molecules to daughter cells during ...

The coordinated termination of DNA replication is an important step in the life cycle of bacteria with circular chromosomes, but has only been defined at a molecular level in two systems to date.

Edited by Richard D. Kolodner, Ludwig Institute for Cancer Research, La Jolla, CA, and approved December 29, 2017 (received for review December 1, 2017) ...

the researchers discovered that PZL-A stabilizes the interaction between mutant POLγ variants and the DNA template during replication. Next, the investigators tested the effects of PZL-A on ...