Streptozotocin (STZ)-induced diabetes in ICR mice is often used to model diabetes mellitus and its complications, as well as other pathologies. In studies of diabetes progression and effects of ...

To further understand the characteristics of de- and trans-differentiation of islet cells, the team performed scRNA-seq of mouse islets in STZ-induced diabetes. ScRNA-seq confirmed the dynamic ...

Genprex, Inc. ("Genprex" or the "Company") (NASDAQ: GNPX), a clinical-stage gene therapy company focused on developing ...

In a streptozotocin (STZ) mouse type 1 diabetes model, analysis of 12,000 genes screened showed that expression of 513 genes increased or decreased significantly in uncontrolled diabetic animals.

Diabetes mellitus disrupts the regulation ... Conducted on female C57BL/6J-OlaHsd mice using a streptozotocin (STZ)-induced model to simulate T1DM, the research focused on critical muscles like ...

The drug candidate SRI-37330 is a non-toxic small molecule that effectively rescued mice from streptozotocin- and obesity-induced diabetes and improved glucose homeostasis. A study published in ...

Wenzhou Medical University researchers have reimagined the spleen as a viable site for islet transplantation, enabling ...

To understand how PGDM affects embryonic cardio-pharyngeal development, diabetes mellitus was induced in female mice using intraperitoneally delivered streptozotocin (STZ) for five days.

The microbiome shapes the development of insulin-producing cells in infancy, leading to long-term changes in metabolism and ...

The drug candidate SRI-37330 is a non-toxic small molecule that effectively rescued mice from streptozotocin- and obesity-induced diabetes and improved glucose homeostasis. A study published in the ...

The drug candidate SRI-37330 is a non-toxic small molecule that effectively rescued mice from streptozotocin- and obesity-induced diabetes and improved glucose homeostasis. A study published in the ...