Mice receiving s-KL showed better coordination in rotarod tests (think of a mouse treadmill), increased endurance in hanging from horizontal bars, and improved grip strength compared to untreated mice ...

Leibowitz described one such experiment, called “RODeo,” which features weekly live-streamed tests using the rotarod device, a widely used tool for assessing mouse endurance and motor function. “Each ...

a) Example of evolution of latencies to fall for a mouse during the accelerating rotarod protocol. Linear regressions estimated values of trial 1 and 7 during each day are shown using green hollow ...

The mouse model carries the Gba1 Leu444Pro point mutation, which is probably the most frequent GBA1 pathogenic variant world-wide. The mouse model shows substantial GCase activity loss, which is seen ...

We have generated a Ctnnb1 germline heterozygous mouse line that displays key features of CTNNB1 syndrome in humans. We have identified novel molecular and functional changes in the brain and a ...

This knock-in (KI) mouse model was generated by introducing a D427V point mutation into exon 10 of the mouse Gba1 (glucosidase, beta, acid 1) gene, which corresponds to the human D409V mutation (The ...

Rotarod testing was conducted on Days 30 and 90 post-injections. Animals were gently placed on top of the rod in a rotarod device and allowed to explore the rotarod for several minutes without ...

Trackball mice can help with wrist pain but they’re also great for small desks and tight spaces. Here's everything you need to know about a trackball mouse.

Exercise Assay Exercise performance was assessed with a mouse RotaRod device (Ugo Basile; catalog No. 47650). The protocol used provided for a progressive increase in speed from 5 rpm to 40 rpm.