In frame translation initiation sites within coding sequences drive the expression of N-terminally truncated proteoforms.

Yale researchers have created "Ochre," a genomically recoded organism that enables the production of synthetic proteins with ...

Oligonucleotide therapies are among the most promising biological therapeutics. They target disease at a different stage of ...

When Xiao Wang applied to faculty jobs, many of the institutions where she interviewed thought her research proposal - to ...

Synthetic biologists from Yale were recode the genetic code of an organism, a novel genomically recoded organism (GRO) with ...

Aneuploidy is frequent in cancer, but in vitro it triggers multiple cellular stresses and often delays proliferation. Through ...

RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which is read by ribosomes to generate protein (translation). Biologically active RNAs ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...

The fatty membrane surrounding every living cell is a vibrant environment where countless biological processes take place.

Postdoctoral scholar Daniela Soto has earned a prestigious fellowship from HHMI with eight years of funding to study the ...

Scientists from the Cancer Dependency Map (DepMap) at the Broad Institute of MIT and Harvard and Columbia University have ...

Sunburn has traditionally been attributed to UV-induced DNA damage, but it turns out that this is not the full truth.