The primary function of the nucleolus is as the site of ribosome-subunit biogenesis in eukaryotic cells. The initial ribosomal RNA (rRNA) precursor is transcribed by RNA polymerase I and is ...

The ribosomal subunits are assembled in the nucleolus and are transported to ... functional connectivity of the different steps in RNA biogenesis in relation to nuclear export is therefore still ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

It's difficult because there are so many moving parts." The situation has created a rather unusual phenomenon; the new Stellaris Biogenesis DLC currently sits with a 'mostly negative' average ...

For example, although ribosomes depleted of small ribosomal subunit protein eS26 (RPS26) stays functional in the cell, they are translating preferentially selected mRNAs (Ferretti et al., 2017; Yang ...

Background: Multiple myeloma (MM) is a biologically heterogeneous malignancy of clonal plasma cells, often progressing from MGUS or smoldering MM. It causes anemia, bone lesions, and immune ...