A somatic ribosomal protein mutation can therefore promote the transformation of cancer but will not be sufficient on its own to cause it. They and mutations in ribosome biogenesis factors can ...

Here, we review the current understanding of ribosome biogenesis and heterogeneity within a neuron. We highlight the mechanisms and local parameters that influence stochasticity in ribosomal ...

Taken together, our data show that in HL H2A.B has acquired a new function, the ability to increase ribosome biogenesis. The eutherian testis‐specific histone variant H2A.B is aberrantly expressed in ...

FIGURE 4. Visualization of plant S6Ks signaling network. Schematic representation of the downstream TORC1/S6Ks signaling events, which control transcription, translation, and ribosomal biogenesis. The ...

Establishment of translational competence represents a decisive cytoplasmic step in the biogenesis of 40S ribosomal subunits. This involves final 18S rRNA processing and release of residual biogenesis ...

Ribosome biogenesis is a complex and energy-demanding process requiring tight coordination of ribosomal RNA (rRNA) and ribosomal protein (RP) production. Given the extremely high level of RP synthesis ...

The yellow cells, indicated by arrows, are the first evidence of increased ribosome biogenesis in cells during epithelial-to-mesenchymal transition (EMT). [Vincent et al.] Researchers from Uppsala ...

Owing to the enormous complexity of the ribosome, the assembly process employs upwards of 200 non-ribosomal biogenesis factors that function transiently. The first structure that results from pre ...

The conversion of ribosomal DNA to ribosomal RNA (rRNA), i.e., transcription, is thought to be a rate-limiting step of biogenesis (the slowest step that determines the speed of the ribosome biogenesis ...

"The relatively compact phenotype of the 90S pre-ribosome gave us the idea that this shell, in combination with other factors, encloses the smaller of the two ribosomal subunits during biogenesis ...

During eukaryotic ribosome formation, a large number of biogenesis factors catalyse the intricate assembly of ribosomal RNA (rRNA) and ribosomal proteins into the two ribosomal subunits 1,2,3,4.