Mitochondrial outer membrane permeabilization is often required for activation of the caspase proteases that cause apoptotic cell death. As a consequence, the integrity of the mitochondrial outer ...

In apoptosis, Bcl-2-family proteins regulate the barrier function of the mitochondrial outer membrane (MOM), controlling the release of proapoptotic proteins from the intermembrane space into the ...

Removing mitofusins from the outer mitochondrial membrane inhibits fusion and prevents abnormal mitochondria from reintegrating into the network, thereby facilitating mitophagy. 47 This so-called ...

Mitochondria, the power plants of the cell, make massive contributions to the energy supply of the body by burning metabolites with the help of oxygen. This cellular respiration takes place in the ...

Mitochondria definition. Mitochondria (mitochondrion, singular) are membrane-bound organelles found in the cytoplasm of almost all eukaryotic cells but are absent in prokaryotic cells. The main ...

A new study reveals that the protein MTCH2, which is essential in a variety of cellular processes, is responsible for shuttling various other proteins into the membrane of mitochondria. The ...

Mitochondria are double membrane bound cytoplasmic organelles present in most eukaryotic cells. They are responsible for aerobic respiration, which they achieve through oxidative phosphorylation.

The data support the findings that heterologous expression of the Leu335Pro variant is sufficient to decrease basal mitochondrial membrane potential and increase respiration, consistent with a ...

Outer membrane Similar to the cell's membrane, this is a fatty layer that contains a number of proteins. These include porins, which allow smaller molecules to cross the membrane freely.

Formation of pores in mitochondrial membrane elucidated. University of Freiburg. Journal Nature Structural & Molecular Biology DOI 10.1038/s41594-022-00897-2 ...

Mitochondria are specialized cellular structures that power various functions. ... the outer membrane is more porous and is less selective about which materials it lets in.

Cellular respiration of the inner mitochondrial membrane. Mitochondria, the power plants of the cell, make massive contributions to the energy supply of the body by burning metabolites with the ...