Birmingham scientists have identified essential genetic code for a method called plasmid curing, which aims to ‘displace’ antibiotic resistance genes from bacteria. Plasmids, which are small, circular ...

A further danger lies in the development of drug resistance in these organisms ... 2.3. Plasmid Profiling Plasmid extraction was done using a QIAprep Spin miniprep kit (Qiagen, GmbH, Germany). A ...

John Innes Center researchers and partners used a model plasmid called RK2 that is used globally to study clinically relevant plasmids that transmit antimicrobial resistance. The study ...

This work will interest those working on plasmid transfer and antimicrobial resistance. Antimicrobial resistance (AMR ... The DNA was then purified using the GeneJet PCR Purification Kit (Thermo ...

Our results strongly suggest a selective role of methotrexate for virtually any antibiotic resistance determinant when present together with trimethoprim resistance on a multi-drug resistance plasmid ...

Libraries were constructed using a rapid multiplex barcoding kit (catalog number SQK-RBK004 ... and implementing these methods in real-time to control the spread of plasmid-borne antimicrobial ...

This important study addresses the challenge of antimicrobial resistance by targeting plasmid proteins that interfere with plasmid ... The DNA was then purified using the GeneJet PCR Purification Kit ...

CRISPR-Cas9 is a bacterial immune system, which we use to “immunize” bacteria from antibiotic resistance genes. Nevertheless, we are still using an engineered plasmid to deliver this to the ...