To protect themselves from powdery mildew, barley has evolved a series of immune receptors that each recognize matching, strain-specific powdery mildew proteins known as effectors. This ...

About Portage Biotech Portage Biotech is a clinical-stage immuno-oncology company advancing a pipeline of novel biologics to transform the immune system’s ability to fight cancer. For more information ...

Portage Biotech (PRTG) presented new preclinical data for PORT-7, a selective Adenosine A2B receptor inhibitor. The new data demonstrate both ...

Portage Biotech unveils new preclinical data on PORT-7, showing strong antitumor effects in mesothelioma and advancing plans for clinical trials.

Muscles and glands are called effectors. The diagram summarises how information flows from receptors to effectors in the nervous system. Receptors are groups of specialised cells. They detect a ...

Most classes of cell-surface receptors are appreciated to signal via various proximal effector molecules. Until recently, an exception to this rule was 7TMRs, which had been viewed as a simple on ...

A novel mouse model offers definitive evidence that a single inhibitory receptor family governs the critical natural killer cell functions of licensing and missing-self.

Distinct sets of chemokines and their receptors are responsible for directing lymphocyte movements in the course of T cell development, antigen-driven differentiation into memory and effector T ...