Researchers from the University of Eastern Finland, Aalto University and the University of Oulu have developed a new ...

Researchers have identified two natural compounds, patulin and xestoquinol, as new inhibitors of the enzyme topoisomerase 1, ...

BP1 is a key player in DNA repair and together with BRCA1 regulate selection of DNA double strand break repair mechanisms. Localization of DNA repair factors to sites of DNA damage by 53BP1 is ...

The human genome is like a big ball of yarn, made up of 3 billion molecular units arranged in sequence and then wrapped up ...

The study tracks mammoth evolution over a million years using mitogenomes, showing shifts in diversity and lineage tied to ...

Historically, small molecule drugs have been precisely designed down to the atomic scale. Considering their relatively large complex structures, nanomedicines have lagged behind. Researchers argue ...

TAL61 demonstrated significant anti-tumor properties with strong tolerability in patient-derived xenograft models of chordoma ...

A team was able to edit the DNA of Lactobacillus strains directly without a template from other organisms. This technique is indistinguishable from natural variation and enabled the researchers to ...

The human genome is like a big ball of yarn, made up of 3 billion molecular units arranged in sequence and then wrapped up ...

Ingrida Domarkienė, a geneticist at Vilnius University in Lithuania, discusses the exciting developments made possible by ...

However, extracting and purifying DNA from FFPE samples presents challenges, potentially causing DNA fragmentation, low yield, or low quality. Furthermore, FFPE extraction protocols are often ...