This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

Methodological advances have enabled discoveries of RNA polymerase interactions with ... roles of these interactions in gene regulation and eukaryotic cellular stress responses, and highlights ...

RNA polymerase II elongation complex (EC ... The nucleosome is the fundamental repeating unit of chromatin in eukaryotes. In ...

Chemists at UCL and the MRC Laboratory of Molecular Biology have demonstrated how RNA (ribonucleic acid) might have ...

Chemists at UCL and the MRC Laboratory of Molecular Biology have demonstrated how RNA (ribonucleic acid) might have ...

Chemists have demonstrated how RNA (ribonucleic acid) might have replicated itself on early Earth -- a key process in the origin of life.

Large-scale comparison of gene families across 1154 Saccharomycotina genomes revealed that gene gains and losses drive yeast ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

AbbVie is paying ADARx Pharmaceuticals $335 million upfront to secure options on next-gen small interfering RNA (siRNA) therapeutics across several disease areas. The collaboration and license ...

In higher eukaryotes, a vast variety of RNAs is transcribed from genomic DNAs. The transcribed RNAs are subjected to RNA processing steps, such as splicing, ...

Researchers engineered a new gene system in the parasite A. deanei using a bacteriophage enzyme and novel drug markers. This ...