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Five of these are core subunits which form crab claw shapes with DNA at their centres, channels for RNA products and NTP substrates as well as an additional 5 units. The claw like shape stabilizes ...
For instance, bacteria contain a single type of RNA polymerase, while eukaryotes (multicellular organisms and yeasts) contain three distinct types. In spite of these differences, there are ...
The prokaryotic form of RNA polymerase has four subunits capable of transcribing all types of RNA. In eukaryotes, these enzymes have eight or more subunits that facilitate the attachment and ...
During transcription initiation, a large, multi-molecular machinery assembles on the promoter of a gene, to enable proper positioning of the RNA Polymerase enzyme and commence accurate mRNA synthesis.
In the latest shake-up for scientific dogma, research has demonstrated that eukaryotic cells can convert RNA sequences back into DNA, through a misunderstood, ‘error-prone’ polymerase. Historically, ...
Despite polα–primase being the first human polymerase discovered, the way it synthesizes very specific lengths of RNA and DNA in a single strand remained unclear for more than 50 years.
This time, they uncovered the first programmable RNA-guided system in eukaryotes. Just a few months ago, the Zhang lab adapted a contractile injection system, found naturally in bacteria ...
Researchers show that polymerase theta can efficiently convert RNA sequences back into DNA, a feat more common in viruses than eukaryotic cells. Editor's Note: Thomas Jefferson University issued ...
Both prokaryotes and eukaryotes respond to the same RNA structure, initiating protein synthesis and thereby defying longstanding expectations. Prokaryotes and eukaryotes, it was long believed ...
as well as a primase to assemble a short RNA primer. The DNA polymerase enzymes involved in the eukaryotic DNA replication belong to the B family of DNA polymerases, whereas those enzymes that ...
The prokaryotic form of RNA polymerase has four subunits capable of transcribing all types of RNA. In eukaryotes, these enzymes have eight or more subunits that facilitate the attachment and ...