At the heart of this method lies the Bst DNA polymerase, whose enzymatic properties—such as strand displacement activity, thermostability, and catalytic efficiency—are critical to the success ...

When RNA molecules are synthesized by cells — a critical process in the creation of proteins and other cellular functions — they typically undergo a series of “folding” events that determine their ...

Through international collaboration, researchers at KAIST have revealed that RNA editing plays a crucial role in regulating neuroinflammation, a key pathology of Parkinson's disease. KAIST ...

Through international collaboration, researchers at KAIST have revealed that RNA editing plays a crucial role in regulating neuroinflammation, a key pathology of Parkinson's disease. The paper is ...

This revolution is being powered by RNA technology — and Canada is uniquely positioned to lead it. While the swift development of COVID-19 vaccines appeared to be a sudden scientific triumph ...

Stanford Medicine researchers have developed a blood test capable of detecting cancers, the ways cancer resists treatments and tissue injury caused by non-cancerous conditions. The new test ...

Get Instant Summarized Text (Gist) A long-read RNA sequencing dataset comprising 750 million reads across 14 human cell lines enables direct observation of full-length RNA molecules, overcoming ...

“Instead, we discovered that these phosphorylation sites work together but have distinct and opposing effects on RNA polymerase II elongation speed and the output of RNA.” The study used a ...

Like mRNA, the majority of lncRNAs are polyadenylated and transcribed by RNA polymerase II. Loci that produce lncRNAs have many features similar to protein-coding genes, promoters, alternative ...

But even though these firsts took place during the pandemic, mRNA vaccines had been in development for many years before COVID-19 emerged as a threat. Looking forward, they'll likely continue to ...

Daiichi Sankyo is stepping up its interest in RNA therapies, teaming with Nosis Biosciences to design drug candidates capable of reaching targets beyond the liver. The Japanese drugmaker is best ...

Now, researchers used cryoelectron microscopy (cryo-EM) to elucidate the structure of the Nipah virus polymerase complex ... for both transcription and RNA replication and mutations that have ...