The lymph nodes, spleen, tonsils and Peyer’s patches are examples of secondary lymphoid tissue. Chronic inflammation can lead to the development of tertiary lymphoid tissue.

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Mastectomy (removal of the entire breast, sometimes with lymph node dissection-removal of the lymph nodes in the armpit) can also follow. Mastectomy may or may not be followed by radiation therapy.

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When the body fights an infection or injury, lymph nodes sometimes swell. Doctors call this a reactive lymph node. Treatment can depend on the cause. Lymph nodes house white blood cells.

Lymph nodes are part of the body’s immune system. A swollen lymph node in the armpit may be a sign of a bacterial or viral infection, an injury, or a serious health condition, such as cancer.