1-Hydroxyphenazine (1-HP) is a virulence factor produced by Pseudomonas aeruginosa. In this study, supercoiled plasmid DNA was employed as an analytical tool for the detection of ROS generation ...

SAN FRANCISCO — Patients with bronchiectasis and a Pseudomonas aeruginosa infection receiving gremubamab, a bispecific monoclonal antibody, vs. placebo had several improved outcomes, according ...

It is empirically known that anionic polyelectrolytes present in cystic fibrosis (CF) airways due to bacterial infection significantly decrease the activity of cationic antimicrobials via ...

Colistin became available for clinical use in the 1960s, but was replaced in the 1970s with other antibiotics owing to its toxicity. [1, 4, 13] There are two forms of colistin available in the ...

Despite intensive research efforts, the aetiology of the majority of chronic lung diseases (CLD) in both, children and adults, remains elusive. Current therapeutic options are limited, providing only ...

The human pathogen Pseudomonas aeruginosa is the leading cause of hospital-acquired infections and, moreover, is resistant to commonly used antibiotics. P. aeruginosa uses the cell-to-cell ...