Kelly Spill didn’t cry when she was diagnosed with stage III rectal cancer at age 28. She held her emotions together when her surgeon told her that she might not be able to carry another baby ...

For a limited group of cancer patients who have solid tumors in the stomach, rectum, esophagus and other organs, an immunotherapy trial offered stunning results. By Gina Kolata When a person ...

These cells, called cancer-associated fibroblasts (CAF), play an important role in how the cancer develops. Several types of CAF stimulate the growth of cancer cells and contribute to the cancer ...

In patients with active cancer and venous thromboembolism, whether extended treatment with a reduced dose of an oral anticoagulant is effective in preventing recurrent thromboembolic events and ...

Mirvetuximab soravtansine shows no significant HRQoL detriments despite TEOEs in FRα+ platinum-resistant ovarian cancer patients. The phase 3 MIRASOL trial confirms improved progression-free and ...

A new mRNA vaccine could prevent pancreatic cancer from returning — potentially for the long haul. In a small clinical trial, some patients who received the vaccine remained cancer-free for more ...

Cancer-associated fibroblasts (CAFs) are crucial in melanoma metastasis, influencing tumor microenvironments and patient outcomes, especially in immunotherapy contexts. Single-cell RNA sequencing ...

Tumorigenicity: Recent studies have shown that cancer associated fibroblasts (CAFs) in the tumor microenvironment can produce both estrogen and progesterone which can promote tumorigenic process ...

Cancer-associated fibroblasts (CAFs) are an important component in solid tumors. They play a decisive role in cancer development and have a significant influence on the success of therapy.

A study provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes their different immunomodulatory roles in the tumor environment.

The results of newly reported research in human cells and in mice, carried out by scientists at Johns Hopkins Kimmel Cancer Center, suggest that age-related changes in fibroblasts contribute to ...