The hyperproliferation of smooth muscle cells and deposition of collagen in the pulmonary artery are among the primary characteristics of pulmonary hypertension (PH). These processes contribute to ...

Knockout of INTS12 improved latency reactivation at the transcriptional level and is more specific to the HIV-1 provirus than AZD5582 & I-BET151 treatment alone. We found that INTS12 is present on ...

The annual Cozzarelli Prize acknowledges papers that reflect scientific excellence and originality. The 2024 awardees will be recognized at an awards ceremony during the NAS Annual Meeting in April ...

We looked for sequences that matched each HML-2 provirus in the genome and found 37 different HML-2 proviruses that were still active. All 54 tissue samples we analyzed had some evidence of activity ...

Domestic fowl produce piRNAs targeting ALV from one ALV provirus that was known to render its host ALV resistant. This proviral locus does not produce piRNAs in undomesticated wild chickens. Our ...

Whether or not splicing at these sites contributed to apparent IRES function in previous studies merits investigation. All provirus plasmids were derived from pACE-GFP, which contains a full-length ...