How do bacteria, lacking a nucleus, organize and pack their genome into the cell? Supercoiling enables this but forces a different kind of transcription and translation in prokaryotes. Aa Aa Aa ...

More information: Dongying Wu et al, A metagenomic perspective on the microbial prokaryotic genome census, Science Advances (2025). DOI: 10.1126/sciadv.adq2166 ...

Testing shows that Evo 2 accurately predicts the functional effects of mutations across prokaryotic and eukaryotic genomes. It also successfully annotated the woolly mammoth genome from raw ...

In contrast, the DNA of prokaryotic cells is distributed loosely around the cytoplasm, along with the protein synthesis machinery. This closeness allows prokaryotic cells to rapidly respond to ...

There are, of course, the standard prokaryotic, yeast and mammalian leagues. Within the last few years, a number of expansion leagues have been added, including Baculovirus and specialized spin-offs ...

Eukaryotic cell DNA in a nucleus, plasmids are found in a few simple eukaryotic organisms. Prokaryotic cell DNA is a single molecule, found free in the cytoplasm; additional DNA is found on one or ...