For decades, scientists have searched for a way to outsmart Lyme disease, a stealthy infection that affects nearly half a ...

Three rare, fatal Creutzfeldt-Jakob disease cases were reported in Hood River County, Oregon. Two people have died. There's ...

In the fight against diseases like Alzheimer’s and Parkinson’s, scientists have long struggled to predict how certain ...

Our project focuses on analyzing how proteins assemble on membranes using Atomic Force Microscopy. With high-resolution, fast-scan Atomic Force Microscopy, we will directly visualize the structure and ...

Prions are best described as misfolded proteins with an ability to transmit their misfolded shape onto normal variants of the same protein. Let's dive into the many fatal neurodegenerative ...

In TSEs the normal cellular prion protein (PrP C) is transformed into an infectious disease-associated isoform, PrP Sc — a potential target for immunotherapy. In the March 6 Nature, Anthony R. White ...

Such a demonstration has, in the past, been called the gold standard of "proof" that infectious protein particles, or prions, free of nucleic acids, are the culprit in transmissible spongiform ...

Gerstmann-Sträussler-Scheinker disease and prion protein cerebral amyloid angiopathy add two more ... which is made of 3R tau and thus lacks the R2 domain. In the P301T case, a structure similar to ...