also called Creutzfeldt-Jakob disease (CJD), results from the misfolding of a normal prion protein—an essential protein present in everyone. The misfolded form of the protein, the cause of CJD ...

Researchers have developed a laboratory model that mimics the pathological aggregation of TDP-43, a key protein in ALS and ...

particularly for advancing the understanding of the mechanism of protein misfolding in prion diseases and other neurodegenerative disorders.” “I knew at a very young age,” Karn said, “that I wanted to ...

Dysfunctional Family. A family tree of tau folds now incorporates two new structures—P301L, P301T (bottom)—and fills in ...

Sangamo Therapeutics, Inc. misses on earnings expectations. Reported EPS is $-0.11 EPS, expectations were $-0.09. Operator: Good afternoon, and welcome to the Sangamo Therapeutics Fourth Quarter ...

The abnormal folding of the prion proteins leads to brain damage and a family ... The fact that amyloid proteins behave like prions, in their ability to induce misfolding of normal proteins, have led ...

A new study reveals a possible protein misfolding mechanism that may resolve a long-standing mystery of why certain proteins refold into unexpected patterns. Proteins are long molecules that must fold ...

A new study has described a potential mechanism that could help explain why some proteins refold in a different pattern than expected. The research showed that a type of misfolding, called non ...