Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

Glucagon-like peptide-1 receptor agonist (GLP-1 RA) medications for weight loss are significantly transforming the fiel ...

Future Microbiol. 2013;8(11):1431-1451. Platelet GPIIIa, and even the same epitope within this surface protein, are also targets of autoantibodies, which are generated in HIV-infected patients.

When thrombin was generated by the blood coagulation reaction, the platelets were activated by the thrombin through the thrombin receptor PAR-1 pathway. Such platelets could greatly contribute to the ...

Megakaryocytes (MKs), known for their role in platelet production ... The review emphasizes the expression of immune receptors by MKs, such as toll-like receptors (TLRs), Fc gamma receptors ...

Megakaryocytes (MKs), known for their role in platelet production ... The review emphasizes the expression of immune receptors by MKs, such as toll-like receptors (TLRs), Fc gamma receptors ...

IPA: Inhibition of platelet aggregation; iv.: Intravenous. The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or ...

This review will provide some recent progress of the use of platelet concentrates to treat lesions on maxillofacial tissues. Subjects: We reviewed the mechanisms by which PCs promote wound healing and ...

PAR1 is a high-affinity receptor for thrombin, whereas PAR4 is a low-affinity ... with many claiming that PAR4 function is confined mostly to platelets. A recent study from our lab identified low ...

COX-1 indicates cyclooxygenase-1; GPVI, glycoprotein VI; PAR1, protease-activated receptor-1; PDE, phosphodiesterase ... identified PAR4 polymorphisms that confer a proatherothrombotic platelet ...