A promising new malaria drug target has been identified in a family of proteins in a malaria-causing parasite.

The disease is caused by five species of Plasmodium parasites, with Plasmodium falciparum responsible for the most severe cases. In 2024 alone, malaria accounted for more than 250 million cases ...

Finally, we also show the frequency dependency of ring-synchronized and unsynchronized blood samples, which can constitute the basis for development of a point-of-care and laboratory-free method to ...

The research team, from the London School of Hygiene and Tropical Medicine, instead looked at the Plasmodium falciparum parasite – which is regarded as the deadliest parasite to humans.

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is published in Life Science Alliance. ‘Phagocytosis of Plasmodium falciparum ring-stage parasites predicts protection against malaria’ by Fauzia Musasisa et al. is published in Nature Communications.

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Abstract: The gametocytes of the malaria parasite Plasmodium falciparum are highly resistant to antimalarial drugs. Its presence in the blood can be detected even after a successful malaria treatment.

In 2022, nearly 619,000 global deaths due to malaria were caused by Plasmodium falciparum, the most virulent, prevalent, and deadly human malaria parasite. For decades, the parasite's resistance ...