Mutations that render Plasmodium falciparum invisible to the current ... testing of samples via more precise methods, like microscopy or detecting the parasite by DNA, to confirm that a negative ...

The primary end point was the rate of adequate clinical and parasitologic response at day 42 after the start of treatment with regard to Plasmodium falciparum, after correction for reinfections ...

The disease is caused by five species of Plasmodium parasites, with Plasmodium falciparum responsible for the most severe cases. In 2024 alone, malaria accounted for more than 250 million cases ...

In 2022, nearly 619,000 global deaths due to malaria were caused by Plasmodium falciparum, the most virulent, prevalent, and deadly human malaria parasite. For decades, the parasite's resistance ...

Parasite Clearance in Patients with Plasmodium vivax or P. falciparum Malaria Treated with Multiple 400-mg Doses or a Single 800-mg Dose of KAF156. Most patients had at least one adverse event.

Plasmodium falciparum, responsible for severe forms, is found mainly in Sub-Saharan Africa, where a child dies of malaria every two minutes. In 2021, 247 million cases and 619,000 deaths were ...

To protect themselves from that fate, the parasites deploy grappling hooks called PfEMP1 (plasmodium falciparum erythrocyte membrane protein 1) onto the outside of the red blood cells, latching ...