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For nearly 40 years, synthetic DNA has been produced using phosphoramidite chemistry, which facilitates the sequential addition of new bases to a DNA chain in a simple cyclic reaction. While this ...
Twist shook up DNA synthesis about 7 years ago, when it introduced a method of conducting phosphoramidite chemistry on silicon chips rather than in traditional well plates. More recently ...
With a closed system like SYNTAX, it is a lot easier to control how the platform is being used and what is synthesized on it than the current systems that use phosphoramidite chemistry ...
The development of solid phase phosphoramidite chemistry has enabled scalable oligonucleotide synthesis, which, coupled with advances in sequencing technology, bolstered the ability of scientists to ...
With a simple reaction, called phosphoramidite chemistry, strings of A, T, C and G, nucleotides can be created in any desired order, one base after another. While the early methods focused on ...
It’s high time – scientists have been stuck with the same old phosphoramidite chemistry and its inherent limitations in length, speed, accuracy and environmental impact for too long. There has been ...
The gold standard for DNA writing, phosphoramidite chemistry, works incredibly well on short, uncomplicated, oligos. For longer stretches of DNA, which may contain DNA with complex features such ...