This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...

Cell lines were grown from NCI DTP frozen stocks in RPMI-1640 supplemented with phenol red ... the RNA was degraded by adding 1 N NaOH (1.5 μl) and incubating at 70 °C for 10 min.

This valuable study focuses on defining how the HSP70 chaperone system utilizes J-domain proteins to regulate the heat shock response-associated transcription factor HSF1. Using a combination of ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. AAVPureMfg produces high-purity AAV vectors ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Microenvironmental mechanical signals significantly influence ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Previously, several works have reported the use of NMs to treat ...

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Following the hydrolysis of the acid, the solution was allowed to cool to room temperature before sodium hydroxide was added to neutralize it. After that, distilled water was added to bring the final ...