To provide updated guidance regarding neoadjuvant chemotherapy (NACT) and primary cytoreductive surgery (PCS) among patients with stage III-IV epithelial ovarian, fallopian tube, or primary peritoneal ...

FAP, fibroblast activation protein; FAPI, fibroblast activation protein inhibitor; TME, tumor microenvironment; CAFs, cancer-associated fibroblasts; NFs, normal fibroblasts; α-SMA, α-smooth muscle ...

associated with intensified ligand–receptor (LR) communication between cancer and fibroblast cells. Experimentally, we confirmed that endocrine therapy induces the upregulation of compensatory ERBB ...

Multivitamin (MV) use is common among men with prostate cancer (PC). However ... yrs after survey completion. Current MV use was associated with lower risk of PC recurrence (basic model: HR 0.52, 95% ...

Brain metastases often occur as a result of advanced cancer and, despite medical innovations, are still associated with a poor prognosis. Now, an international expert committee led by the Medical ...

Copyright: © 2025 The Author(s). Published by Elsevier Ltd.

MOE Key Laboratory of Macromolecule Synthesis and Functionalization of Ministry of Education, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, PR China ...

Methods: Primary lung fibroblasts from IPF patients and controls were cultured and treated with various ITCs to identify potential senolytic agents. Senescence-associated β-galactosidase staining, ...