Osteoblasts act in a group ... life to maintain bone architecture balance and systemic mineral homeostasis. During this "remodeling" process, osteoclasts remove mineralized bones, whereas ...

Bone-destructive diseases such as osteoporosis and chronic inflammatory arthritis affect millions of people worldwide, ...

Bone mass and strength are maintained by the bone remodeling cycle involving the integrated actions of osteocytes, osteoclasts and osteoblasts. Current therapies for the prevention and treatment ...

The imbalance occurs between osteoblasts, responsible for bone formation, and osteoclasts, which break down bone tissue. This ...

Treatments target abnormal osteoclast activity but face adherence issues. The disease disrupts the balance between bone ... mitochondrial health influence osteoblast differentiation.

The imbalance occurs between osteoblasts, responsible for bone formation, and osteoclasts, which break down bone tissue. This disrupted process results in weakened bones and increased ...

“Bone is a highly active organ, undergoing continuous osteoblast-induced bone formation and osteoclast-mediated bone resorption throughout life,” the authors explained. “The process of bone ...

Osteoclasts are cells in the body that play a role in breaking down old bone tissue. Osteoblasts then play a role in the formation of new bone tissue. Multiple myeloma can upset the balance of ...

Reducing circulating estrogen levels increases osteoclast activity and, therefore, bone loss. 9 Not only is the balance of osteoblasts and osteoclasts altered, but the microenvironment of the ...