A team of researchers from APL and the Johns Hopkins Bloomberg School of Public Health is developing next-generation brain organoid platforms to better understand the effects of mild blast-induced ...

Alzheimer’s disease (AD) is a prevalent neurodegenerative disorder marked primarily by β-amyloid (Aβ) deposition and abnormal ...

Scientists from Cincinnati Children's and colleagues based in Japan report achieving a major step forward in organoid ...

Scientists from Cincinnati Children's and colleagues based in Japan report achieving a major step forward in organoid ...

Boston Children's Hospital scientists have unveiled a five-day approach to generate functional vascular organoids capable of supporting blood flow and in vivo engraftment.

For instance, IL-2, IL-7, IL-15, and IL-21 are essential for immune cell culture, while Wnt3a, EGF, Noggin, and R-spondin-1 form the most classical cytokine scheme in organoid culture.

Cytokines designed for organoid culture Image Credit: Sino Biological Inc. Highlighted products WENR (Wnt3a / EGF / Noggin / RSPO1) is organoid culture's most familiar cytokine scheme.

The researchers then sent a bunch of tumor organoid models of leukemia, colon cancer and breast cancer into space with the private Axiom Mission 1. They found that the models also grew ...