Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered a new way ...

Obesity causes temporary disruptions, but not permanent structural changes, in the liver’s molecular network that regulates ...

They found that mice lacking the cystathionine γ-lyase enzyme experienced the most significant weight loss, nearly 31%, on ...

Blocking Mitch, a protein that regulates energy control, prevents fat from accumulating in human cells. About a decade ago, a ...

According to scientists, humans could become 'immune to obesity' if we can 'delete' a protein in our bodies. With obesity ...

Researchers at the Tohoku University Graduate School of Medicine have uncovered a key primary step in the hepatic ERK pathway ...

Obesity is associated with skeletal deterioration and increased fracture risk, but the underlying mechanism is unclear. Herein, it is shown that obese gut microbiota promotes skeletal deterioration by ...

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering ...

"An exciting finding was when we tried to treat the obese mice with colon inflammation by lowering their inflammation, it actually stopped the ERK pathway in the liver from activating," explains Imai.

The researchers developed a thorough series of experiments to determine if colonic inflammation due to obesity could impact ...