(74) Ketterer et al. mimicked the nuclear pore complex using DNA origami rings modified with the proteins in the natural nuclear pore complex. In this study, the authors characterized the ...

The approach is demonstrated by its application to the assembly process of the nuclear pore complex in the context of the nuclear ... Finally, these snapshot models are selected and connected into a ...

Nuclear pore complexes (NPCs) form gateways that control molecular ... To begin to answer these questions, we have used DNA origami to build a cylinder that mimics the dimensions of the central ...

Several types of cancer are believed to be linked to alterations of macromolecular structures known as nuclear pore complexes (NPCs ... enable the synthesis of DNA. Whether NPC alterations ...

researchers have been fascinated by the three-dimensional structure and function of these nuclear pores, which act as guardians of the genome: substances that are required for controlling the cell are ...

makes copies of its DNA, and much more. Among those pieces of machinery, and one of the most complex, is something known as the nuclear pore complex (NPC). The NPC, which is made of more than 1,000 ...

We uncover that C‐circles bind to the nuclear pore complex (NPC) and to the SAGA‐TREX2 complex, similar to other non‐centromeric episomal DNA. Disrupting the integrity of the SAGA/TREX2 complex ...

The nucleus is guarded by a highly secure door, the so-called nuclear pore, that controls the transport of substances from the cytoplasm to the cell nucleus and back. A research group at the ...

Nuclear pore complexes and ribosomal DNA are typically excluded during conventional macronucleophagy and micronucleophagy, indicating that degradation of nuclear cargo is tightly regulated. In mammals ...

We show that co-expression of NDPK-A during transient expression results in improved transfection efficiency in CHO cells, presumably due to enhanced transportation of plasmid DNA into the nucleus via ...

Nuclear pore complexes are the 'doors' that all materials pass through to gain entry to the cell's nucleus. Because cancer cells are rapidly growing and dividing they need and create more nuclear ...