Selective transport through the nuclear pore complex presents a very complicated case—a lot of ins, a lot of outs, a lot of what-have-yous. To have any hope of unraveling the case, scientists ...

The nuclear pore is a protein-lined channel in the nuclear envelope that regulates the transportation of molecules between the nucleus and the cytoplasm. In eukaryotic cells, the nucleus is ...

Researchers have long wondered how nuclear pores -- the all-important channels that control the flow of information in and out of a cell's nucleus -- double in number to prepare for the split to ...

They knew that in yeast, Ndc1 is embedded in the nuclear envelope and is needed for the insertion of both nuclear pore complexes and spindle pole bodies. But because cells are so sensitive to ...

Several types of cancer are believed to be linked to alterations of macromolecular structures known as nuclear pore complexes (NPCs). These structures are embedded in the nuclear envelope, a ...

Nuclear pores are essential elements of all cells ... many nuclear transport channels are assembled into a given nuclear envelope remain unclear. Here, we report that depletion of the NPC basket ...

This transport of large goods is similar to how large macromolecules are trafficked out of the cell nucleus via an export pathway termed nuclear envelope budding ... out of the nucleus by bypassing ...

UNSW medical researcher Dr. David Jacques and his team have discovered how the human immunodeficiency virus (HIV) breaches the cell nucleus to establish infection, a finding that has implications ...

This microscopic metropolis relies on an intricate gateway - facilitated by nuclear pore complexes (NPCs) within the nuclear envelope - to control its molecular traffic.

Researchers at Kanazawa University report in Cell Reports how alterations in the nuclear pores lead to the degradation of anti-tumor proteins. Several types of cancer are believed to be linked to ...