Early research shows that editing expanding trinucleotide repeats halts the lengthening process that causes neurological ...

In a leap forward for genetic and biomedical research, two scientists at the University of Missouri have developed a powerful ...

Genetic mutations occur everyday in our cells, but the vast majority of them are repaired. New research finds DNA repair is not on PAR in HD cells, causing mutations to build up in people with HD.

illuminate how Pol-theta undergoes a major structural rearrangement when it binds to broken DNA strands. By unveiling Pol-theta's DNA-bound structure-its active state-the study provides a ...

illuminate how Pol-theta undergoes a major structural rearrangement when it binds to broken DNA strands. By unveiling Pol-theta's DNA-bound structure—its active state—the study provides a ...

Our bodies are made up of about a hundred million million (100,000,000,000,000) tiny cells. You can only see them under a microscope. Cells group themselves together to make up the tissues and organs ...

In normal human ... enclose the DNA. There are some natural processes that can damage DNA. For example, in chromothripsis, which occurs in some cancers, the chromosomes are broken and rearranged.

which leads to changes in the NEAT1 secondary structure. As a result, highly methylated NEAT1 accumulates at some of these lesions to drive the recognition of broken DNA. In turn, experimentally ...

"When you squeeze a balloon, your fingers form tunnels in its structure ... broken DNA," says Mekhail. The findings have significant implications for some cancer treatments. Normal cells use ...

The natural ends of chromosomes appear alarmingly like broken DNA, much as a snapped ... prevents telomerase from interfering with DNA repair under normal circumstances. He ultimately found ...

The natural ends of chromosomes appear alarmingly like broken DNA, much as a snapped ... prevents telomerase from interfering with DNA repair under normal circumstances. He ultimately found ...

Mutations disrupting POT1's interaction reveal its role in preventing harmful DNA damage responses and maintaining chromosome end structure ... t want to keep dividing with broken DNA. That’s what ...