Casali's team also started with immunodeficient mice (NSG W41 mutants), injecting human stem cells purified from umbilical cord blood through the animal's left ventricle. After a period of weeks ...

The Jackson Laboratory imported the strain in 2015 in anticipation of distribution, but has since discontinued production of MISTRG mice. Fortunately for the research community, both the NSG ...

Results show that the team created a new mouse breed, called NSG-Pro, that produces levels of human prolactin similar to those in patients with metastatic estrogen receptor-positive breast cancer.

A new study published in Microbiology Spectrum reports the establishment of a liver-humanized NSG-PiZ mouse model that is fully permissive to hepatitis B virus (HBV) infection. In this model, HBV can ...

Preclinical studies in NSG mice to compare Kiji’s therapeutic to WT-MSC treatment showed, at 21 days, that the CXCR4/IL-10 treated mice had gained approximately five percent of their body weight ...

Peripheral blood T cell subset phenotype analysis in melanoma patients treated with combination nivolumab + ipilimumab compared to ipilimumab alone. Updates on phase1b/2 trial of the indoleamine ...

Out of these eight strains of mice, only the CAST mouse was susceptible to SARS-CoV-2, including beta, omicron and delta variants. The eight strains include A/J, B6J, CAST, 129S1, NSG, NZO, PWK ...

The study explored eight genetically diverse mouse strains, including A/J, B6J, CAST, 129S1, NSG, NZO, PWK, and WSB, encompassing traits like type 1 and type 2 diabetes susceptibility, obesity ...

Casali's team began with injecting immunodeficient NSG W41 mutant mice intracardiacally (left ventricle) with human stem cells they purified from umbilical cord blood. After a few weeks ...

This new mouse model, called NSG-Pro, supports greatly enhanced growth of implanted ER-positive human breast cancers. Molecular pathway analyses of the tumors revealed that prolactin collaborates ...