Research led by the National Institute of Biological Sciences in Beijing has discovered that switching on a single dormant ...

Such genetically engineered mouse models (GEMMs) provide excellent experimental systems to develop a deeper understanding of cancer biology in vivo and are increasingly being used for preclinical ...

The authors previously developed a mouse model ABab-A2 transduced with complete human TCR gene loci and HLA-A*02:01, termed ABab-A2 mice.

Boston Children's Hospital scientists have unveiled a five-day approach to generate functional vascular organoids capable of supporting blood flow and in vivo engraftment.

However, the HLA-A2 mice used were not tolerized to the foreign human mesothelin peptide presented in the SCT, making these data less translationally relevant.