A study led by a physician-scientist at the University of Arizona College of Medicine–Tucson's Sarver Heart Center identified ...

Red blood cell-derived extracellular vesicles in type 2 diabetes are actively taken up by the endothelium, transferring the ...

Researchers reviewed how air pollution, especially fine particulate matter (PM2.5), drives the development and worsening of ...

Axon guidance cues direct nerves in the heart during development, disease and regeneration. These cues determine cardiac innervation patterning by regulating the balance between chemo-attraction and ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. During gastrulation, mesodermal cells derived ...

The study uses genetic knockout models to investigate how Slit2, Slit3, Robo1, and Robo2 contribute to cardiac innervation. Using constitutive and cell type-specific knockout mouse models, they show ...

Professor Patrick Vallance, Centre of Clinical Pharmacology, Gower Street Campus, 3rd Floor, Rayne Institute, 5 University Street, London WC1E 6JJ, UKpatrick.vallance{at}ucl.ac.uk If you wish to reuse ...

The transcription factor HIF1A is activated by disturbed blood flow in arteries and contributes to early atherosclerosis by promoting endothelial cell (EC) glycolysis and inflammation. The related ...

revealed that H-151 can inhibit the cGAS-STING-IRF3 pathway and inflammatory responses in cardiac macrophages during myocardial ... the pathway sets off a chain of pathological processes. In ...

After decades of hype and setbacks, scientists have made impressive progress into tricking stem cells into repairing organs.