This result suggested a higher activity for most of the “private” genes in the thymus when compared to the peripheral compartments. Altogether, we provide a unique resource to inform future studies, ...

This important study utilizes humanized mice, in which human immune cells are introduced into immune-deficient mice, to provide convincing evidence that two helper CD4 T-cell subsets, T-follicular ...

Background: The murine model of cerebral aneurysm (CA) serves as a prevalent tool for investigating the molecular underpinnings of CA. However, the extent to which the CA murine model aligns with that ...

Hypertension and Vascular Research Unit, Lady Davis Institute for Medical Research, Quebec, Canada (O.B., P.P., E.L.S.). Hypertension and Vascular Research Unit, Lady ...

Hematopoietic stem cells (HSCs) are generated from specialized endothelial cells, called hemogenic endothelial cells (HECs). It has been debated whether HECs and non–HSC-forming conventional ...

Here authors describe the immune pathology of the murine disease model by single-cell ... migrate from the thymus to the intestines after birth where they can develop into unconventional ...