thymic tissue does. For binding assays, monoclonal antibodies to human CD18 (L130, mouse IgG1), CD3 (UCTH1, mouse IgG1), CD45 (H130, mouse IgG1), CD71 (M-A712, mouse IgG2a), CD11c (LeuM5 ...

All model parameter estimates were obtained based on published physiological data of thymocyte dynamics and thymus properties in mouse and human ... cells to peripheral lymphoid tissues such as the ...

Conventional T cells that recognize peptide antigens presented by the major histocompatibility complex (MHC) undergo well-characterized processes of antigen receptor rearrangement followed by positive ...

A recent study reveals that age plays a significant role in the outcomes of intermittent fasting. Researchers from Technical ...

A recent study reveals that age plays a significant role in the outcomes of intermittent fasting. Researchers discovered that chronic intermittent fasting disrupted the development of ...

Understanding why newborns, but not adults, can regenerate the heart could lead to treatments that "reprogram" adult ...

There is potential for Tregs and amphiregulin to be used in patients receiving cancer therapies to ameliorate immune function.

A team of international researchers led by scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States, with its National Medical ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

LOS ANGELES--(BUSINESS WIRE)--A team of international researchers led by scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United ...