A team of scientists at Duke University made a mouse just a bit more human. They didn’t give it speech or opposable thumbs.

Researchers at the Francis Crick Institute have shown that gonadotrophs, cells in the pituitary gland with a key role in ...

Memorial Sloan Kettering Cancer Center investigators report that T cell interferon-γ (IFNγ) orchestrates a dendritic-cell–natural-killer-cell circuit that suppresses leptomeningeal metastases in mouse ...

As people age, their immune systems become less efficient, posing a challenge for cancer therapies that rely on harnessing ...

We measured the amounts of IL-2, IL-4, IFN-γ and IL-10 produced by T ... of mouse immunoglobulin G2a in the expression plasmid pmIgV (G.Z., unpublished data), and was transfected into CHO cells.

An engineered viral protein enhanced the anticancer function of T cells in mice, suggesting a new strategy to improve ...

Here the authors use both patient data and a mouse glomerulonephritis model to show that increased type I interferon may expand a subset of pro-inflammatory T cells for subsequent kidney pathology.

In recent years, the therapeutic landscape for hematological malignancies has undergone a profound transformation, driven by ...