We used the SCID-hu (Thy/Liv) mouse model ... in the anti-CD3 and costimulated cultures in every experiment (Fig. 4). Thus latently infected cells generated in the thymus after infection with ...

Nevertheless, some mature T cells could develop in the thymus, and these populated the periphery through homeostatic proliferation. a conformational change in the intracellular portion of CD3 ...

The discovery reveals the role of a growth factor and endothelial cells in thymus repair, and could have implications for chemotherapy and radiation patients’ recovery following treatment. The study’s ...

By studying the effects of the nasal anti-CD3 in a mouse model of TBI, researchers found the spray could reduce damage to the central nervous system and behavioral deficits, suggesting a potential ...