A new study suggests that stem cells thought to be dormant may offer clues to why our sense of smell declines or is lost.

Background Idiopathic pulmonary fibrosis (IPF) is a progressive disease of lung parenchymal scarring that is triggered by ...

But when the researchers imaged slices of living neonatal mouse lung over three days, a different view emerged, one of a ballooning outgrowth of epithelial cells supported by a ring of ...

Interestingly, the team also discovered that the epithelial cells try and ... in this mouse model of neutrophilic asthma. More information: Vijay Raaj Ravi et al, Lung CD4+ resident memory T ...

To try to answer that question, the scientists from VUMC and Michigan revisited gene activity datasets from IPF patients and a mouse model of repeated lung injury. The team found that the abnormal ...

This approach enabled over 70% editing efficiency in mouse lung stem cells ... function in primary patient-derived bronchial epithelial cells equivalent to Trikafta for F508del, corrected ...

In the new study, they found gadolinium was able to prevent epithelial cell damage, inflammation and mucus secretion in the mouse lung tissue, suggesting that it could be a new treatment option ...

A new Yale-led study has found that stem cells migrate to help repair damaged lung cells caused by injuries such as viral or bacterial infections. The findings were published Feb. 19 in the journal ...

When transplanted into the airways of a mouse model of airway epithelial lung injury, these basal cells demonstrated lifelong engraftment. In other words, they remained in the airways and were able to ...

In their second paper, "Durable alveolar engraftment of PSC-derived lung epithelial cells into immunocompetent mice," CReM researchers targeted the lung air sacks, known as alveoli. Kotton and his ...

A team of researchers from the Netherlands, Germany and the U.S. reports that two drugs show promise in rejuvenating lung epithelial progenitor cells damaged ... human and mouse lung tissue ...

The mouse ACE2 does not do so ... It has been assumed that Type 2 (AT2) lung epithelial cells are infected by SARS-CoV-2 as a result of its ACE2 expression, though at a low level, leading to ...