Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages—the white blood ...

Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse embryonic fibroblasts without using stem cell technology.

Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse ...

The fibroblasts were directly converted into iPULs (induced pulmonary epithelial-like cells)—functionally akin to native AT2 ...

UCLA researchers have successfully grown miniature lungs from stem cells—complete with their own functioning blood vessel ...

Ace was shown to be primarily expressed by lung endothelial clusters 1 and 2 (Fig. 5c), in agreement with what is known about lung Ace expression. To test whether alveolar macrophages are capable of ...

Abstract —The effects of transfer of the endothelial nitric oxide synthase (eNOS) gene to the lung were studied in mice. After intratracheal administration of AdCMVβgal, expression of the ...

Researchers have created a comprehensive spatiotemporal atlas of the developing mouse lung, providing unprecedented insights into the molecular and cellular processes that shape this vital organ ...

Interspecies variations in lung anatomy, physiology, and immune responses can hinder full reproducibility of results. An additional limitation is that our study omitted measurements of drug ...

Red blood cells carry oxygen from the lungs to every other organ, and blood-forming stem cells must make about 200 billion new red blood cells each day to keep the oxygen flowing. For many years, ...

Using a four-dimensional microscopy technique, researchers have created 3D video images of mouse lung tissue grown in the laboratory. What they have learned has been nothing short of groundbreaking.