Cold' tumors are resistant to common immunotherapies. Researchers have uncovered a master regulator that can be manipulated to prevent tumor growth in mice.

Experiments in mice infected with the SARS-CoV-2 virus revealed that the immune cell class in question, called nerve and ...

Scientists have discovered that a rare immune cell type in the lungs, called NAMs, plays a crucial role in surviving COVID-19 ...

A research team led by the Guangzhou Institutes of Biomedicine and Health of the Chinese Academy of Sciences has constructed a comprehensive spatiotemporal atlas of developing mouse lungs, revealing ...

Nine out of 10 unvaccinated people exposed to an infected person will catch it, and once measles takes root, the virus can damage the lungs, kidneys and the brain. Unlike viruses that require ...

The cell-type specific function of Piezo1 in PH was assessed in (1) PASMCs and lung tissues from patients with PH and (2) 2 mouse strains characterized by smooth muscle cell–specific, conditional ...

A novel mouse model of arthritis with high homocysteine levels developed heart diastolic dysfunction and reduced lung compliance, mimicking human disease. Selective activation of FPR2 by BMS986235 ...

Department of Pediatrics, Columbia University, New York, NY, United States Collectively, these findings suggests that Mtb survival hinges on its ability to manipulate host macrophage metabolism. By ...

Relative to other infected mouse lines, a more severe ALI was observed in KO, 1A 0, and 6A 2 mice. Reduced viral titers were generally observed in the lungs of infected SP-A mice relative to KO mice.