Research led by the Department of General and Visceral Surgery, Faculty of Medicine, University of Freiburg, Germany has ...

In the distal ileum, FXR, activated by bile acids, induces expression of the FGF19 gene in humans. ... The authors caution that human and mouse bile acid profiles differ in important ways.

In studies in mice, researchers report they have found that bilirubin, a bile pigment most commonly known for yellowing the skin of people with jaundice, may play an unexpected role in protecting ...

The drug improved bile composition and reduced inflammation and fibrosis in a mouse model by targeting two ABC transporters, ABCB4 and BSEP. Rectify Pharma is using its ABCs to treat PSC.

Bile duct cancer is a rare but aggressive form of cancer, affecting just over 2,000 people in the UK every year. However, incidences of bile cancer are steadily increasing every year – with some ...

Bile acids are molecules produced by the liver and used by the gut to help digest food and absorb cholesterol, fats, and nutrients. In 2019, Evans and his colleagues showed in mice how high-fat ...

Mouse study hints at how bile acid recycling could affect gut bacteria. Mouse study hints at how bile acid recycling could affect gut bacteria. Skip to main content. Thank you for visiting nature.com.

Wednesday, July 24, 2024. News & Perspective Drugs & Diseases CME & Education Drugs & Diseases CME & Education ...

Treatment of mouse hepatocytes with the reconstituted bile acid mixture induced significant pro-inflammatory responses without affecting the cell viability.

Bile duct cancer is a rare but aggressive form of cancer, affecting just over 2,000 people in the UK every year. However, incidences of bile cancer are steadily increasing every year – with some ...